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Index > Protein center > SLC2A2(Gene name) > Human
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  • SLC2A2 (Gene name),
  • Solute carrier family 2, facilitated glucose transporter member 2 (Protein name ),  GTR2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SLC2A2(GLUT2);
    Protein name:
    Solute carrier family 2, facilitated glucose transporter member 2;
    Alternative:
    Glucose transporter type 2, liver(GLUT-2);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    524
    Sequence:
    50:
    MTEDKVTGTL | VFTVITAVLG | SFQFGYDIGV | INAPQQVIIS | HYRHVLGVPL | 
    100:
    DDRKAINNYV | INSTDELPTI | SYSMNPKPTP | WAEEETVAAA | QLITMLWSLS | 
    150:
    VSSFAVGGMT | ASFFGGWLGD | TLGRIKAMLV | ANILSLVGAL | LMGFSKLGPS | 
    200:
    HILIIAGRSI | SGLYCGLISG | LVPMYIGEIA | PTALRGALGT | FHQLAIVTGI | 
    250:
    LISQIIGLEF | ILGNYDLWHI | LLGLSGVRAI | LQSLLLFFCP | ESPRYLYIKL | 
    300:
    DEEVKAKQSL | KRLRGYDDVT | KDINEMRKER | EEASSEQKVS | IIQLFTNSSY | 
    350:
    RQPILVALML | HVAQQFSGIN | GIFYYSTSIF | QTAGISKPVY | ATIGVGAVNM | 
    400:
    VFTAVSVFLV | EKAGRRSLFL | IGMSGMFVCA | IFMSVGLVLL | NKFSWMSYVS | 
    450:
    MIAIFLFVSF | FEIGPGPIPW | FMVAEFFSQG | PRPAALAIAA | FSNWTCNFIV | 
    500:
    ALCFQYIADF | CGPYVFFLFA | GVLLAFTLFT | FFKVPETKGK | SFEEIAAEFQ | 
    524:
    KKSGSAHRPK | AAVEMKFLGA | TETV
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    SMR:
    MIM:
    UniGene:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
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    ELISA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
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    ELISA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
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    ELISA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
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    Packing:
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    CLIA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
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    CLIA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
    Cat.:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
    Cat.:
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    Please sign in first.
    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
    Cat.:
    U9059r
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    MSDS:
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    Polyclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
    Polyclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
    Polyclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
    Cat.:
    P9059Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
    Polyclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
    Cat.:
    P9059Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
    Cat.:
    P9059Rb-r
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
    Monoclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
    Monoclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
    Monoclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
    Monoclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
    Monoclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
    Protein for Human Solute carrier family 2, facilitated glucose transporter member 2
    Protein for Human Solute carrier family 2, facilitated glucose transporter member 2
    Protein for Human Solute carrier family 2, facilitated glucose transporter member 2
    Protein for Human Solute carrier family 2, facilitated glucose transporter member 2
    Protein for Human Solute carrier family 2, facilitated glucose transporter member 2
    Protein for Human Solute carrier family 2, facilitated glucose transporter member 2

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    References
    1. 1.
      "Sequence, tissue distribution, and chromosomal localization of mRNA encoding a human glucose transporter-like protein."
      Fukumoto H. , Seino S. , Imura H. , Sieno Y. , Eddy R.L. , Fukushima Y. , Byers M.G. , Shows T.B. , Bell G.I.
      Proc. Natl. Acad. Sci. U.S.A.85:5434-5438(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT LEU-68
      tissue: Kidney.
      tissue: Liver.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Liver.
    3. 3.
      "The DNA sequence, annotation and analysis of human chromosome 3."
      Muzny D.M. , Scherer S.E. , Kaul R. , Wang J. , Yu J. , Sudbrak R. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , more...
      Nature440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "Sequence variations of the pancreatic islet/liver glucose transporter (GLUT2) gene in Japanese subjects with noninsulin dependent diabetes mellitus."
      Matsubara A. , Tanizawa Y. , Matsutani A. , Kaneko T. , Kaku K.
      J. Clin. Endocrinol. Metab.80:3131-3135(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 29-100 (ISOFORM 1);VARIANTS LEU-68 AND ILE-110
      tissue: Peripheral blood.
    6. 6.
      "Variability of the pancreatic islet beta cell/liver (GLUT 2) glucose transporter gene in NIDDM patients."
      Tanizawa Y. , Riggs A.C. , Chiu K.C. , Janssen R.C. , Bell D.S.H. , Go R.P.C. , Roseman J.M. , Acton R.T. , Permutt M.A.
      Diabetologia37:420-427(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT NIDDM ILE-197;VARIANT ILE-110
    7. 7.
      "A mutation in the Glut2 glucose transporter gene of a diabetic patient abolishes transport activity."
      Mueckler M. , Kruse M. , Strube M. , Riggs A.C. , Chiu K.C. , Permutt M.A.
      J. Biol. Chem.269:17765-17767(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANT NIDDM ILE-197;CHARACTERIZATION OF VARIANT ILE-110
    8. 8.
      "A mutation in GLUT2, not in phosphorylase kinase subunits, in hepato-renal glycogenosis with Fanconi syndrome and low phosphorylase kinase activity."
      Burwinkel B. , Sanjad S.A. , Al-Sabban E. , Al-Abbad A. , Kilimann M.W.
      Hum. Genet.105:240-243(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT FBS LEU-417
    9. 9.
      "Mutation analysis of the GLUT2 gene in patients with Fanconi-Bickel syndrome."
      Sakamoto O. , Ogawa E. , Ohura T. , Igarashi Y. , Matsubara Y. , Narisawa K. , Iinuma K.
      Pediatr. Res.48:586-589(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS FBS PRO-389 AND GLU-423
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